Depends. My loved one is a sexual being in canon so it doesn't bother me in general, but some characters and situations make me angry because I can't imagine it happening or if it's a a bad situation for anybody involved. So really most things beyond vanilla sex bother me, actually. That said I don't get mad for days or anything, although it may annoy me for more than a few minutes.
Makes me wonder, though. Does anyone here have a waifu who is confirmed not a virgin and was not raped, and they have issues with her having vanilla, in-character sex in fanart/doujin? Or even the canon, and she's enjoying herself...? Because seeing that makes me happy (it doesn't always turn me on) and sometimes I wonder if I'm the odd one out in this case.